
Yes. oak wilt moves to other trees, which is why one infected tree is a decision about the whole yard rather than about that tree. A red oak showing symptoms is usually lost within a season. The urgent job is protecting the oaks around it, because it moves underground through grafted roots.
Rapid wilting from the top down in summer, leaves dropping while still half green, often one side of the canopy first.
Present in Indiana and the reason for the pruning rule below. It's the single best argument against 'we'll just tidy the oak up in June'.