Answered for Pittsboro, Hendricks County.
Common on stressed honey locust and on trees with mower or string-trimmer damage at the base — which is a genuinely avoidable cause. In Pittsboro, two completely different tree populations in one small town: the original grid near Meridian and Main carries full-size 80-100 year old shade trees over the roofline, while the post-1997 subdivisions that hold most of Pittsboro's houses are still on 20-to-30-year-old nursery stock planted at the ordinance minimum of 2.5-inch caliper. No municipal tree inventory or canopy study for Pittsboro was found, so species dominance is inferred from housing age and the UDO's planting standards rather than measured. A canker that has girdled more than about half the trunk circumference is structural, not cosmetic.
Two completely different tree populations in one small town: the original grid near Meridian and Main carries full-size 80-100 year old shade trees over the roofline, while the post-1997 subdivisions that hold most of Pittsboro's houses are still on 20-to-30-year-old nursery stock planted at the ordinance minimum of 2.5-inch caliper. No municipal tree inventory or canopy study for Pittsboro was found, so species dominance is inferred from housing age and the UDO's planting standards rather than measured.
Sunken dead patches on bark, sometimes oozing, often with cracked margins. Branches above the canker die back.
A canker that has girdled more than about half the trunk circumference is structural, not cosmetic. Small branch cankers can be pruned out; trunk cankers usually can't.
Prune out affected branches in dry weather, well below the canker.
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Distance measured from Pittsboro.