
Listed as susceptible in the urban ice-storm tables and cited across multiple studies as one of the highest-risk genera, because very fast growth produces low-density brittle wood. Under ice or a summer straight-line wind it sheds limbs of a size that goes through a roof rather than just denting it, and that single fact is the reason most cottonwood quotes get written at all.
Cottonwood needs deadwood removal on a recurring cycle rather than a one-time cleanup, because it manufactures deadwood faster than anything else here. Never top it: it decays rapidly through large wounds, and a topped cottonwood regrows dense, weakly attached sprouts on a decaying stub, which is a materially worse hazard than what was there before.